A Prospective Randomized Study to Assess the Efficacy of Rate and Site of Atrial Pacing on Long-Term Development of Atrial Fibrillation
Lau Chu-Pak, Wang Chun-Chieh, Tachapong Ngarmukos, Kim You-Ho, Kong Chi-Woon, Omar Razali, Charn Sriratanasathavorn, Munawar Muhammad. Kam Ruth, Lee Kathy LF, Lau Elizabeth Oi-Yan, Tse Hung-Fat, SAFE Study Steering Committee for the SAFE Study GroupInstitute of Cardiovascular Science and Medicine, Honorary Professor in Medicine, Division of Cardiology, Department of Medicine, Room 1927, 19/F, Block K, Queen Mary Hospital, Pokfulam Road, Hong Kong. Fax: 852-2818-6304; E-mail: cplau@hkucc.hku.hk
บทคัดย่อ
The Septal Pacing for Atrial Fibrillation Suppression Evaluation (SAFE) study is a single-blinded, parallel randomized designed multicenter study in pacemaker indicated patients with paroxysmal atrial fibrillation (AF). The objective is to evaluate whether the site of atrial pacing–-conventional right atrial appendage versus low atrial septal—with or without atrial overdrive pacing will influence the development of persistent AF. The study will provide a definitive answer to whether a different atrial pacing site or the use of AF suppression pacing or both can give incremental antiarrhythmic benefit when one is implanting a device for a patient with a history of paroxysmal AF.
ที่มา
ปี 2552, September
ปีที่: 20 ฉบับที่ 9 หน้า 1020-1025
