Systemic sclerosis (SSc) is a connective tissue disease characterized by autoimmune overactivation, microvascular endothelium damage and excessive collagen deposition, leading to disability of organ systems in the body, especially hand disability and deformity. The purpose of the pilot study was to determine the immediate effects of traditional Thai massage on alteration of hand temperature and hand functions in patients with scleroderma. Twelve volunteers participated in this study and were divided into 2 groups. The experimental group (n = 6) were treated by traditional Thai massage on the upper limbs for 30 minutes. (15 min on each side). The control group (n = 6) rested in supine position for 15 minutes. Alteration of hand temperature was recorded by Thermography, whereas hand functions were measured by Hand Mobility in Scleroderma (HAMIS). The results showed that the experimental group showed significant increase hand temperature when compared with the control group (P < 0.05). Hand functions in the experimental group also showed significant improvement (P < 0.05) when compared with the control group. In conclusion, traditional Thai massage could increase hand temperature and improve hand function in patients with scleroderma. This manual modality may be used as an adjuvant therapy for scleroderma patients.