This study is to compare the electrical energy when modified electroconvulsive therapy was performed by using induction agents of thiopentone and propofol. Forty patients (ASA physical status I and II) were included and randomly divided into two groups, each group contained twenty patients and were given either thiopentone 3.0 mg/kg or propofol 1.5 mg/kg as induction agents. The duration of seizure in propofol group was significantly shorter than thiopentone group (25.90 ± 6.54 and 37.20 ± 9.13 sec respectively). The number of patients needed increased electrical energy stimulation was more in propofol than thiopentone groups.