Purpose: To compare visual outcome after applying wavefront-guided customized ablation with conventional ablation in laser in situ keratomileusis (LASIK) patients.Methods: We performed a prospective, randomized controlled study that included 22 eyes of 11 patients who were treated with LASIK using the Nidek EC-5000 excimer laser system. We applied wavefront-guided customized ablation (study group) in the first eye of each patient. The conventional ablation (control group) was performed in the other eye of the same patient. Best spectacle-corrected visual acuity (BSCVA), spherical equivalent refraction, and high-order aberrations were evaluated preoperatively and at 1 month. High-order aberrations were measured using the Nidek OPD-Scan.Results: Preoperative and 1-month postoperative BSCVA were better than 20/40 (100%) after LASIK with both conventional ablation (control) and wavefront-guided customized ablation. Preoperatively, mean high-order aberrations in the control group were 0.572 and in the study group, 0.428 (Zernike coefficient unit). One-month after LASIK, mean high-order aberrations in the control group were 0.496 and in the study group, 0.476 (Zernike coefficient unit). We found no statistically significant difference between preoperative and 1-month postoperative high-order aberrations in either group.Cconclusion: LASIK with both conventional ablation and wavefront-guided customized ablation resulted in the same BSCVA 1 month after LASIK. Preoperative and 1-month postoperative high-order aberrations were not statistically different following LASIK between ablation types.

ปี 2545, May-June ปีที่: 18 ฉบับที่ หน้า S332-S335